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ATYPICAL NEVUS


  
 Atypical Nevus?? What's that?

Mole

Your dermatologist has told you that a pathologist described a growth on your skin as an “atypical nevus”. You may ask, “Just what is a nevus, and what does ‘atypical’ mean? Is it dangerous for my health? Was all of it removed? Could it return and become something worse?”


Nevus - Mole

The words nevus and mole are often used to describe a dark spot in the skin. Moles may be present at birth or develop later in life. Acquired moles are a form of benign neoplasm, while congenital moles are considered a minor malformation, or hamartoma. Moles are most often of no medical consequence, but they may be removed for cosmetic or other reasons. Moles are usually circular or oval and not very large. Most infants are born with moles, and almost everyone has at least one or two moles on their bodies. Large numbers may be concentrated on the back, the chest and arms.

Dysplastic Nevus

Dysplastic nevi or dysplastic nevus syndrome is a condition describing a person with a large quantity of moles, some of them larger than normal and/or atypical.

This condition is associated with a higher risk of malignant melanoma. More than half of malignant melanomas arise 'de novo', rather than from a pre-existing nevus.

Nevertheless, since atypical nevi are at a higher risk of evolving into a malignant melanoma, they need to be checked regularly for any changes in appearance.

Atypical

The major reason your doctor sends a sample of a mole to a laboratory is to rule out the possibility of a melanoma. The laboratory may report your mole to be dysplastic or atypical and have some “architectural disorder” but without enough features to call it a melanoma. A nevus is also described as a Clark’s nevus or a dysplastic melanocytic nevus.

Moles, known medically as nevi, are clusters of pigmented cells that often appear as small, dark brown spots on your torso, face, arms and legs. But moles can come in a range of colors and can develop virtually anywhere, including your scalp, armpits, under your nails, and between your fingers and toes.

Most people have between 10 and 40 moles, although the number you have may change throughout life. New moles can persist into mid-adulthood, and because moles last about 50 years, some moles may disappear as you age.

The great majority of moles are harmless, but in rare cases, moles may become cancerous. Monitoring moles and other pigmented patches is an important step in the diagnosis of skin cancer, especially malignant melanoma. Although not all melanomas develop from pre-existing moles, many begin in or near a mole or other dark spot on the skin.

Although the typical mole is a plain, brown spot, moles come in a wide variety of colors, shapes and sizes. They can be flesh-colored, reddish-brown, medium to dark brown, or blue; they may vary in shape from oval to round, and be as small as a pinhead or large enough to cover an entire limb.

Moles that are larger than 8 inches in diameter and present at birth are a special problem. They may need to be removed to avoid the risk of malignant melanoma, the most deadly form of skin cancer.

The surface of a mole can be smooth or wrinkled, flat or raised. Sometimes a mole may start out flat and brown and later become slightly raised and lighter in color. Some may become raised enough that they form a small stalk; others may simply disappear.

Although most moles develop by age 20, they may continue to appear until midlife. There are also certain
times in your life when moles are more apt to change; for example, they're likely to become darker, larger and more numerous because of hormonal changes during adolescence and pregnancy or with the use of birth control pills.






  
 Freckles and moles: What's the difference?

Freckle

Both freckles and moles are areas of increased pigment (melanin) in your skin. But they are not the same thing.

Freckles are small, flat, pigmented spots on your skin. They vary in color from red to tan to brown. Freckles are not present at birth. Instead, they develop in childhood and in later years as a result of repeated sun exposure. Freckles occur primarily in sun-exposed areas of your body, such as your nose and shoulders.

Moles (nevi) are clusters of pigmented cells (melanocytes). Although they often appear as small, dark brown spots, moles come in a range of colors and sizes. They can be raised or flat and can develop almost anywhere on your body — even between your fingers and toes. Unlike freckles, moles can be present at birth. They often become more prominent with age. Moles also may darken with repeated sun exposure or as a result of hormonal changes in pregnancy.

Freckles rarely develop into skin cancer. However, freckles are especially common in people with light skin, and having light skin that burns easily increases your risk of skin cancer. Also, some skin cancer in its earliest stages resembles a freckle.
If you have a pigmented lesion — whether you think it's a freckle of mole — that changes in size, shape or color, or becomes painful, consult your doctor.


  
 Malignant Melanoma

Persons with dysplastic nevi may have a greater-than-average chance of developing malignant melanoma. These people should be seen regularly by a dermatologist to check for any changes that might indicate skin cancer.

They should also learn to do regular self examinations, looking for changes in the color, size or shape of their moles, or the appearance of new moles.They should also shield their moles from sun exposure using sunscreen and/or clothing.

Frequently difficult to evaluate with the naked eye, the unique features of a malignant nevus can be seen with the help of a microscope. Therefore, any suspected nevus should be removed for microscopic evaluation. In contrast with benign nevi, the typical malignant melanoma is asymmetrical, with irregular borders, measures more than 5mm, exhibits shades of different brown colors, and is elevated above the surface of the skin. Unfortunately, many dysplastic or atypical nevi show similar characteristics. When small, most melanomas are curable with a simple surgical excision.



  
 The A-B-C-D of Melanoma

Recognizing the early warning signs of malignant melanoma is important. Remember the ABCD of melanoma when examining your moles.

 

A-ASYMMETRY:

  • One half of the mole does not match the other half.

B-BORDER:

  • The border or edges of the mole are ragged, blurred or irregular.

C-COLOR:

  • The color of the mole is not the same throughout, or it has shades of tan, brown, black, red, white, or blue.

D-DIAMETER:

  • The diameter of a mole is larger than 6mm, about the size of a pencil eraser.

    If a mole displays any of these signs, it should be checked promptly by a dermatologist.

    If the appearance of a mole worries you or if it changes suddenly in any way, you should consult a dermatologist.